Event:

Neurons in the saccade-related part of the fastigial nucleus
send output to components of the saccade burst
generator in the brainstem. In this project we sought to describe
exactly what saccade-related signals from
the cerebellum normally contribute to burst generator activity. To do
this we have recorded from inhibitory
burst neurons (IBNs) before and during saccade adaptation and from
neurons in the abducens nucleus before and
after blocking saccade-related cerebellar output. Our findings
support the proposal that saccade-related cerebellar
output adds both on- and off-direction activity to contralateral
IBNs. Cerebellar signals increase on-direction IBN
activity early in saccades suppressing antagonist resistance to
saccades. Cerebellar signals increase off-direction
IBN activity late in saccades to end agonist contractions at the right
time.