Event:
| 29.04.2022, 12:00 | Graduate School of Neuroscience | ||
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Event Type:
Talk
Speaker: Thomas Pfeffer Institute: Universitat Pompeu Fabra Title: Neurolunch: Neuromodulatory regulation of large-scale cortical dynamics and perceptual choice in humans |
Location:
GSN Seminar room D00.003 and zoom Großhaderner Str. 2 82152 Martinsried Host: Laura Busse |
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Abstract:
The catecholamine (dopamine and noradrenaline) and cholinergic systems have long been implicated in the regulation of cortical and behavioral state. Influential models postulate distinct computational roles for these systems in the orchestration of cognition and behavior. Yet, direct evidence for dissociated effects on large-scale cortical activity is missing. Through a combination of whole-brain recordings of neural population activity in healthy humans (using magnetoencephalography) and selective pharmacological manipulations, we uncovered distinct roles of catecholamines and acetylcholine in shaping the intrinsic dynamics of large-scale cortical populations and choice behavior. Furthermore, the application of biophysical models allowed us to identify potential neural mechanisms underlying the experimentally observed neuromodulatory effects.
https://lmu-munich.zoom.us/j/98686551920?pwd=ZldobmtkM29BRUZvZjhWRmxXbEZtQT09 Meeting ID: 986 8655 1920 Passcode: 484227 Registration Link: |
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