Event:
| 05.12.2023, 11:00 | Max Planck Institute for Biological Intelligence Campus Martinsried | ||
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until 12:00
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Event Type:
Talk
Speaker: Jens Hjerling-Leffler Institute: Division of Molecular Neurobiology, Department of Medical Biochemistry and Biophysics, Karolinska Institutet Title: The neuroscientist’s guide to schizophrenia: a data-driven prioritization of circuits |
Location:
MPI BI, Seminar room NQ105, Hybrid presentation Am Klopferspitz 18 82152 Martinsried Host: Christian Mayer |
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Abstract:
Understanding the where and when of etiology as well as the cellular and network mechanisms behind the disorder phenotype of psychiatric disorders is imperative for targeted neurobiological research. Integration of genomic insights from genome-wide association studies with single-cell transcriptomics is a powerful approach for the former and single-cell transcriptomics on animal models and postmortem data offers insights into the latter. Dr. Hjerling-Leffler will discuss progress in the investigation in these areas and how the data supports a network model of schizophrenia. Specifically, how large scale genomics, via transcriptomics, agrees with and can inform functional imaging in the prioritization of brain circuitry. The findings underscore the value of single-cell transcriptomics in decoding the polygenicity of psychiatric disorders and offer a promising convergence of genomic, transcriptomic, and brain imaging modalities toward common biological targets.
Zoom link: https://gwdg.zoom.us/j/84472240120?pwd=WGVXUEoxMlZOUnZjMkpUcE5yVCsvZz09 Meeting-ID: 844 7224 0120 Kenncode: 185545 Registration Link: |
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