Event:

Malignant brain tumours are among the most fatal cancers. Despite representing only about 1-2% of all types of cancers, they result in a disproportionately bigger share of cancer mortality. These patients often present with disastrous prognoses despite aggressive multimodal therapy. The complexity of these types of cancers and the urgent need for improved patient outcomes provide the impetus to employ animal models of cancer. While research comparing the phenotype of animal cancers to human cancers has revealed some differences, there are many similarities.
This talk will give a brief review of mouse cancer models in general followed by an example of a xenograft transplantation model incorporating in vivo real time imaging.