Event:

The goal of our laboratory is to control the expansion of neural stem
cells (NSC) and the generation of neurons in the mammalian brain in
order to understand the role of adult neurogenesis in brain function,
behavior and therapy. We found that a transient manipulation of the
length of the G1 phase of the cell cycle of NSC can be used as a means
to increase neurogenesis in development and adulthood(Lange et al.,
2009; Artegiani et al., 2011). Ongoing experiments aim to address
whether or not this acute increase in neurogenesis positively
contributes to brain function, learning, memory or recovery upon injury.
In addition, we use a number of approaches to identify the mechanisms
underlying the physiological proliferation vs differentiation of NSC,
including regulation by long non-coding RNAs.