Event:

A grand goal in brain research is to understand how the interplay of structural, chemical and electrical signals in and between cells gives rise to tissue properties, especially for complex tissues like nervous systems. New technologies are hastening progress as researchers make use of an increasingly powerful arsenal of tools for obtaining multi-scale and multi-modal data, from the level of molecules to whole organs This talk will highlight projects in which development and application of new contrasting methods and imaging tools have allowed us to observe otherwise hidden relationships between cellular, subcellular and molecular constituents of cells, including those of nervous systems. New chemistries for carrying out correlated light and electron microscopy will be described, as well as recent advances in large-scale high-resolution 3D reconstruction combining light, x-ray and electron microcopy.